Hisao's Medical Condition
Posted: Sat May 09, 2009 2:05 am
Hello! first post, but I had some questions on the MCs medical condition. I'm not an expert on cardiac conditions, but I have a lot of knowledge on treatments of various medical conditions. I'm a Biomedical Engineer with a focus on tissue engineering and regenerative medicine, or wound therapy might be a more general term. Again, I'm not an expert, I'm not so much on the patient treatment or after care side as the development of treatments side. however i do need to know what's currently available, and in designing new treatments the ability for the caretaker to use those treatments must be taken into account. But in a nutshell what i want to know is: Why say 'arrhythmia' instead of 'weak heart'? why don't conventional treatments work for the MC if arrhythmia is the main problem? Why was his chest cracked (or scarred)?
While playing through the demo, The first thing i noticed was a large number of inconsistencies very early in the game. After the MC passes out and the scene shifts to the hospital an image of an ECG is displayed. The wave form shown is not a normal heart rhythm (called sinus rhythm). At first i thought this was on purpose, as nearly immediately after it is mentioned the poor bastard has arrhythmia. I was surprised the conditioned was even named, but moving on. The wave form displayed does show a type of arrhythmia. The p wave is missing, but a complete spectrum would need to be seem to complete diagnose the problem, which i'm not really interested in, but i don't like inconsistencies so i'm pointing it out. The p wave indicates the beating of the atrium, during the wave is the atrium contracts, followed by the contraction of the ventricles (The large spike, called the QRS). the final wave is a 'reset' or relaxation phase where nothing is really beating, but an electrical signal is still picked up. The absence of the P wave shows the MCs atrium is not beating. Very good reason to be in a hospital. This type of arrythmia would need to be treated with a pace maker, or a new heart, depending. (The head nurse mentions 'congenital muscle deficiency'. congenital means the problem arose in the fetus, if i remember right. and muscle deficiency would suggest that the basic problem is his heart is too small or weak. Could explain the no-atrium contraction, but no amount of pills will fix or treat that. he would need a new heart, end of story.) It would also cause the ventricular muscles of the heart to beat inconsistently, as it usually looks for the P wave before beating. Muscle efficiency could cause the atrium not to beat, But the arrhythmia briefly described in the text is not this type of arrhythmia, as it focuses on the hear beating too fast. Also the mention of the MC being on beta blockers (saw that somewhere on the forum) is somewhat inconsistent with the missing P wave. This suggests more that he suffers from Atrial or ventricular fibrillation. This is usually treated with a defibrillator. Heparin is also listed in the 'sea of text' that accompany a couple other medicines and side effects etc. Heparin can be used in the treatment of A. Fib. But it is more often used in surgery, as it's a pretty powerful anti coagulant and not really used widely outside of a hospital where you can be watched constantly. Also, it MUST be injected. Heparin degrades when taken orally. an anticoagulant also suggests that he has something implanted. As an anticoagulant would only be needed if there was something his blood could stick to, or he had a blood disorder. Things the blood could stick to would either be an artificial heart valve, or pace maker leads. an anticoagulant could also be used to lower blood pressure, to a degree, but that's not it's primary purpose. Seeing as he has muscle deficiency his cardiac output is likely low. why does he require anti-coagulants? (But i'm not a pharmacologist, but i do know that heparin is way too strong for this kind of disorder) a prescription strength asprin (or acetylsalicylic acid since asprin sounds kind of lame) would be safest. there are stronger ones available, but it seems very odd that heparin would be prescribed. anyway, Most pacemakers nowadays contain both a defib and a pacer. solving two of the previously mentioned problems. This might not work however if the MC had a severely damage heart, meaning the could not do the surgery required. But that is also inconsistent as the mention of scars on his chest. and pacemaker leads are usually installed through the brachial artery, so the scar would be closer to his armpit. If they cracked his chest, then they would have had to repair a ruptured vessel (bypass surgery, he did have a heart attack, but bypass isn't always needed. It doesn't seem Hisao would need that) or installed a heart valve. This type of damage is typically not caused by arrhythmia alone, but also neo-intimal hyperplasia, or overgrowth of the endothelial in a blood vessal, cause the vesal to become compromised and blocking the flow of blood. (there are other causes, but this is more likely considering the age of the MC) A heart valve could be needed if he somehow had compromised valves. possible due to the muscle deficiency. They would not need to crack his chest to diagnosis 'weak heart' as an echo cardiograph would help indicate that, because of very thin heart walls. The most likely explanation i can see is that they cracked his chest to put in new heart valves. which would explain the anti-coagulants and other hoard of medications.
If his heart was severely damaged, he would need a transplant. Considering his age, he would be high on the list. But Japan is well known for it's lack of donors, so that can be explained. However, his parents were willing to sell their house to pay for treatment. The most logical course would be to ship the poor lad to america, most likely california due to it's larger asian population and the fact it's a 'biotech hub'. Furthermore, if his heart was that damaged a large number of medications would not be recommended, as they would further damage the cardiac tissue. Seeing as his heart is already weak, a large number of medications seems very odd. but all of that is inferred, and after reading most of the 'explanation' of the MCs condition, someone like me who has a lot of knowledge is left with "...WTF!?" as there are a large number of inconsistencies in the described treatments, images, and text explanation. so...what exactly is wrong with the guy? because his condition doesn't seem untreatable to someone with more medical knowledge. There is another Doujin game, I think it's come see me tonight but i can't remember, where one of the girls has a similar (less severe) condition i think you are going for. In the end her and the protogonist do end up flying over seas for treatment. It was cute. It's been a long time since i've played that game though, and all i really remember is her hair was blue, she had a scar next to her left breast, and she had a 'rare heart condition.'
The easiest way to 'fix the problem' would be to forego the mention of a disease altogether, and say 'rare heart condition' it's a little lame, but prevents people like me from picking it apart at every detail. also, as he's a highschool student, he likely wouldn't know every detail that was wrong with him. he might only be able to understand the fact that he has a heart condition. Namely, his heart is weak, and he sometimes suffers from arrhythmia as a result. As arrhythmia isn't the real problem, a weak heart is. if that is the case, this should be mentioned somewhere. probably before any attempt to explain the disease instead of after by the head nurse, in a way most people probably won't understand. you may not even mention arrhythmia, because arrhythmia's are VERY treatable and the MC could lead a fairly normal life. He would just need to watch his level of activity, namely intercourse, sports, and on bad days going up and down stairs. a special school wouldn't really be needed. If he lived in a very rural area, he might have to move to a city, but unless he was in danger of having a heart attack nearly every day, he wouldn't need constant nursing. Aka, his heart is EXTREMELY weak, which is likely the case. But as mentioned previously that should be said instead of arrhythmia. I like seeing technical lingo, but it implies certain things about his condition. arrhythmia is emphasized a lot, but that doesn't seem to be the real problem and could confuse someone.
God that's a lot of text. but hopefully it helps you guys out. (and appeases my curiosity)
While playing through the demo, The first thing i noticed was a large number of inconsistencies very early in the game. After the MC passes out and the scene shifts to the hospital an image of an ECG is displayed. The wave form shown is not a normal heart rhythm (called sinus rhythm). At first i thought this was on purpose, as nearly immediately after it is mentioned the poor bastard has arrhythmia. I was surprised the conditioned was even named, but moving on. The wave form displayed does show a type of arrhythmia. The p wave is missing, but a complete spectrum would need to be seem to complete diagnose the problem, which i'm not really interested in, but i don't like inconsistencies so i'm pointing it out. The p wave indicates the beating of the atrium, during the wave is the atrium contracts, followed by the contraction of the ventricles (The large spike, called the QRS). the final wave is a 'reset' or relaxation phase where nothing is really beating, but an electrical signal is still picked up. The absence of the P wave shows the MCs atrium is not beating. Very good reason to be in a hospital. This type of arrythmia would need to be treated with a pace maker, or a new heart, depending. (The head nurse mentions 'congenital muscle deficiency'. congenital means the problem arose in the fetus, if i remember right. and muscle deficiency would suggest that the basic problem is his heart is too small or weak. Could explain the no-atrium contraction, but no amount of pills will fix or treat that. he would need a new heart, end of story.) It would also cause the ventricular muscles of the heart to beat inconsistently, as it usually looks for the P wave before beating. Muscle efficiency could cause the atrium not to beat, But the arrhythmia briefly described in the text is not this type of arrhythmia, as it focuses on the hear beating too fast. Also the mention of the MC being on beta blockers (saw that somewhere on the forum) is somewhat inconsistent with the missing P wave. This suggests more that he suffers from Atrial or ventricular fibrillation. This is usually treated with a defibrillator. Heparin is also listed in the 'sea of text' that accompany a couple other medicines and side effects etc. Heparin can be used in the treatment of A. Fib. But it is more often used in surgery, as it's a pretty powerful anti coagulant and not really used widely outside of a hospital where you can be watched constantly. Also, it MUST be injected. Heparin degrades when taken orally. an anticoagulant also suggests that he has something implanted. As an anticoagulant would only be needed if there was something his blood could stick to, or he had a blood disorder. Things the blood could stick to would either be an artificial heart valve, or pace maker leads. an anticoagulant could also be used to lower blood pressure, to a degree, but that's not it's primary purpose. Seeing as he has muscle deficiency his cardiac output is likely low. why does he require anti-coagulants? (But i'm not a pharmacologist, but i do know that heparin is way too strong for this kind of disorder) a prescription strength asprin (or acetylsalicylic acid since asprin sounds kind of lame) would be safest. there are stronger ones available, but it seems very odd that heparin would be prescribed. anyway, Most pacemakers nowadays contain both a defib and a pacer. solving two of the previously mentioned problems. This might not work however if the MC had a severely damage heart, meaning the could not do the surgery required. But that is also inconsistent as the mention of scars on his chest. and pacemaker leads are usually installed through the brachial artery, so the scar would be closer to his armpit. If they cracked his chest, then they would have had to repair a ruptured vessel (bypass surgery, he did have a heart attack, but bypass isn't always needed. It doesn't seem Hisao would need that) or installed a heart valve. This type of damage is typically not caused by arrhythmia alone, but also neo-intimal hyperplasia, or overgrowth of the endothelial in a blood vessal, cause the vesal to become compromised and blocking the flow of blood. (there are other causes, but this is more likely considering the age of the MC) A heart valve could be needed if he somehow had compromised valves. possible due to the muscle deficiency. They would not need to crack his chest to diagnosis 'weak heart' as an echo cardiograph would help indicate that, because of very thin heart walls. The most likely explanation i can see is that they cracked his chest to put in new heart valves. which would explain the anti-coagulants and other hoard of medications.
If his heart was severely damaged, he would need a transplant. Considering his age, he would be high on the list. But Japan is well known for it's lack of donors, so that can be explained. However, his parents were willing to sell their house to pay for treatment. The most logical course would be to ship the poor lad to america, most likely california due to it's larger asian population and the fact it's a 'biotech hub'. Furthermore, if his heart was that damaged a large number of medications would not be recommended, as they would further damage the cardiac tissue. Seeing as his heart is already weak, a large number of medications seems very odd. but all of that is inferred, and after reading most of the 'explanation' of the MCs condition, someone like me who has a lot of knowledge is left with "...WTF!?" as there are a large number of inconsistencies in the described treatments, images, and text explanation. so...what exactly is wrong with the guy? because his condition doesn't seem untreatable to someone with more medical knowledge. There is another Doujin game, I think it's come see me tonight but i can't remember, where one of the girls has a similar (less severe) condition i think you are going for. In the end her and the protogonist do end up flying over seas for treatment. It was cute. It's been a long time since i've played that game though, and all i really remember is her hair was blue, she had a scar next to her left breast, and she had a 'rare heart condition.'
The easiest way to 'fix the problem' would be to forego the mention of a disease altogether, and say 'rare heart condition' it's a little lame, but prevents people like me from picking it apart at every detail. also, as he's a highschool student, he likely wouldn't know every detail that was wrong with him. he might only be able to understand the fact that he has a heart condition. Namely, his heart is weak, and he sometimes suffers from arrhythmia as a result. As arrhythmia isn't the real problem, a weak heart is. if that is the case, this should be mentioned somewhere. probably before any attempt to explain the disease instead of after by the head nurse, in a way most people probably won't understand. you may not even mention arrhythmia, because arrhythmia's are VERY treatable and the MC could lead a fairly normal life. He would just need to watch his level of activity, namely intercourse, sports, and on bad days going up and down stairs. a special school wouldn't really be needed. If he lived in a very rural area, he might have to move to a city, but unless he was in danger of having a heart attack nearly every day, he wouldn't need constant nursing. Aka, his heart is EXTREMELY weak, which is likely the case. But as mentioned previously that should be said instead of arrhythmia. I like seeing technical lingo, but it implies certain things about his condition. arrhythmia is emphasized a lot, but that doesn't seem to be the real problem and could confuse someone.
God that's a lot of text. but hopefully it helps you guys out. (and appeases my curiosity)