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Hey. I used to work with mentally ill kids, ranging from 6-18 with anything from ADD and bipolar to down syndrome. I am not sure if you are planning to have that type of character in this game, but if you are perhaps I can help a bit. I don't have any experience from the medication and treatment side of it, but I used to be a 'teacher aid' which basically means my job was to keep them under as much control as you could expect a class of such students to be.
Unfortunately I have never worked with anyone who behaves like Misha. The closest that I can think of is a bipolar girl. She would switch between being very happy, much like Misha, but would then be violent and angry. Misha hasn't really shown this side so I don't know if she is like that..