![Image](http://katawa-shoujo.com/res/source.jpg)
I imagine that most of our preconceptions have already been slanted by playing Act 1 through umpteen million times, which is probably why I can't really construe Emi and Rin here as anything else than the genki girl and the stoic girl. If anything, the Emi I see in this picture would have slightly different dialogue, and Rin would be less out there and more just plain aloof.
I don't know if it's because there's a grand total of 1 character smiling on the page, but something about it seems to suggest a rather more darker interpretation of the characters. For instance, Hanako would still be isolated and shy, but more aggressive about her scars. Instead of running away from people, she'd make them run away from her, snapping "What are you looking at?!" and "Leave me alone!" at the drop of a hat. All the while sounding like she's about to burst into tears, though, because while she genuinely doesn't want to hurt people, she doesn't know any other way to deal with her complex.
And Lilly just looks a lot less confident and in control here. While she'd still be a Yamato Nadeshiko oneesama to her class, respected for her mature composure and motherly wisdom, she's also suicidally depressed and prone to nihilistic musings once the protagonists gets her to open up to him. Might also have a fatal condition to go with that blindness.
Shizune would just be a class representative rather than the student council president, and a more traditional take on the trope at that: the class dislikes her for being nosy and overtly serious, and her difficult position is made even more precarious by the fact that she can't speak. Give or take a Misha to adjust angst levels appropriately. Still competitive, she tends to view other people more in the terms of enemies than just opponents, and considers her class a pack of slackers she needs to domesticate into honor students in order to "succeed" at her task.
So what are your two cents?